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Is a Wegovy injection safe?

Do you struggle with your body weight?


Is a Wegovy injection safe?

Do you struggle with your body weight? Then perhaps the FDA approved and NICE approved new weight loss drug, Wegovy, could be the weight loss solution you’ve been looking for.

But wait, an injectable prescription medicine to help you manage your body weight? Is that even safe?

What is Wegovy?

Wegovy is a new medication to aid weight loss. This prescription medicine is injected subcutaneously to help overweight and obese adults reduce their body fat.

This isn’t another one of those herbal weight loss products, this is a FDA approved chronic weight management drug that has been proven to work.

Sound too good to be true? Well, it’s not.

Wegovy works by mimicking the hormones our body produces naturally called GLP 1. This hormone induces insulin secretion after we’ve eaten to regulate appetite, saying to our brains ‘I’m full now’.

Alongside increased physical activity and a reduced calorie meal plan, Wegovy has been shown to aid serious weight loss.

Tackling obesity

Being overweight is one of the biggest killers in the world today. Obesity ranks among the top diseases like heart disease, cancer, and diabetes.

If there was something you could do to make serious lifestyle changes, wouldn’t you do it?

But an injectable prescription medicine? Is it safe?

Well, yes. And it’s one of the best.

There really aren’t many safe weight loss drugs suitable for chronic weight management, and the ones that do exist have a very long list of potential side effects.

Wegovy is the first FDA endorsed subcutaneous weight loss drug approved for chronic weight management since 2014.

What makes it so great?

It is twice as effective as the other weight loss drugs on the market, and it comes with fewer side effects too.

The weight loss benefits of Wegovy

In a 68 week double blind trial of over 2000 overweight and obese adults, most patients lost between 15-20% of their body weight.

They took weekly semaglutide injection 2.4 mg dose, in addition to following a reduced calorie diet and increased physical activity.

The placebo group lost just 2.4% body weight.

Other weight loss drugs have been shown to help patients lose around 5% body weight.

Wegovy gets 3-4X the weight loss results of its closest competitors.

The most important information about Wegovy

While that all sounds too good to be true, it isn’t.

Saying that, Wegovy isn’t without its issues. Like all medicines, it may cause serious side effects, including serious allergic reactions.

Here’s what you need to know.

Who is Wegovy suitable for?

Wegovy is approved by the FDA for people who fall into one of two categories:

Obese adults with a body mass index (BMI) of over 27, plus other weight related medical problems including high blood pressure, or type 2 diabetes.

Obese adults with an initial body mass index (BMI) of over 30.

Wegovy offers obese people an alternative way to lose weight without resorting to extreme measures such as bariatric surgery.

Indications and usage

How do you take Wegovy?

Wegovy is a subcutaneous (under the skin) injectable prescription medicine that requires you to inject yourself in either your upper arm, upper stomach or thigh once a week.

Wegovy is divided into 5 strengths. You’ll initially be given a dose of just 0.25 mg, but you’ll gradually increase your dosage every four weeks until you’re receiving the full dose of 2.4 mg.

Instructions for Use

Before you inject yourself, make sure you know the correct way to inject the pen.

Wegovy is a clear, odourless liquid, so if your injection pen has a liquid that is coloured or cloudy, discard it. It isn’t safe to use.

What other drugs will affect Wegovy?

Wegovy works by slowing your digestion. So if you’re taking other drugs including over the counter medicines, or herbal supplements, make sure you tell your physician, because Wegovy can slow down your body’s ability to absorb these medicines.

Don’t mix prescription drugs

If you’re taking insulin to treat diabetes, including dulaglutin esemetatide, and Liraglutin, you need these medicines to work fast. Don’t mix prescription drugs.

But it’s not just Wegovy that affects other medicines, other medicines such as vitamins and herbal products can impact the way Wegovy works too.

Make sure you tell your healthcare provider about all the medicines you’re taking, before you take Wegovy.

Learn More

Before using Wegovy

Patients with a history of serious hypersensitivity reactions, or who have a personal or family history of thyroid cancer, including a type of thyroid cancer called medullary thyroid carcinoma mtc, should not take this medication.

You should also not take this medicine if you have an endocrine disorder known as multiple endocrine neoplasia syndrome type 2.

Nor should you take it if you’re pregnant, if you’re planning a pregnancy, or if you’re breastfeeding.

Some of the side effects of Wegovy may cause serious complications for patients with the following conditions:

  • Pancreatitis

  • Acute gallbladder disease

  • Low blood sugar

  • Kidney failure or acute kidney injury

  • Diabetic retinopathy

  • Mental health issues

General information about the safe and effective use of Wegovy

We’ve briefly touched on the potential side effects Wegovy can cause above.

But like any weight loss drugs, if you have underlying serious health issues, it can have serious side effects.

For example, it can cause severe adverse gastrointestinal reactions. Which is why you’re prescribed the lowest dose to begin with, slowly building up to the maximum dose of 2.4 mg per week as your body develops a tolerance to the medicine.

Other side effects can include low blood sugar, particularly in patients with type 2 diabetes.

Medullary thyroid carcinoma MTC

Semaglutide, the active drug in Wegovy caused an increased risk of thyroid c cell tumors in animal clinical trials. It’s not known if it has the same effect on humans.

Due to this risk, if you have a personal or family history of medullary thyroid carcinoma mtc, a type of thyroid tumors, this medicine isn’t for you.

Multiple endocrine neoplasia syndrome

Similarly, if you have a personal or family history of multiple endocrine neoplasia syndrome type, a genetic disorder that affects the endocrine system, you are also advised not to take the medicine, as it might cause thyroid cancer.


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