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Wegovy vs Ozempic

Which is better for weight loss: Wegovy vs Ozempic?


Which is better for weight loss: Wegovy vs Ozempic?

If you struggle with obesity – a weight related comorbid condition, and no matter how hard you try, you simply can’t lose weight, then you might want to try a weight loss drug to help you.

Ozempic is the most well known weight loss medicine available to purchase, but its manufacturers have been working on a new, improved formulation, specifically created for weight loss – Wegovy.

So what’s the difference between the two and which is better for weight loss?

What is the difference between Wegovy and Ozempic?

Ozempic and Wegovy are two of Novo Nordisk’s injectable weight loss medication brands.

When used in conjunction with a reduced calorie diet and increased physical activity, they aid weight loss, helping patients lose a significant amount of weight.

But neither of them started life as a weight loss medicine. In fact, Ozempic started life as a type-2 diabetes medicine.

When the manufacturers realised that the active ingredient, Semaglutide, was highly effective at helping patients lose weight, the company renamed and marketed the drug under the weight loss brand name, Ozempic.

So where does Wegovy fit in?

Well, Wegovy contains a much stronger dose of semaglutide than Ozempic.

While Ozempic can also be used to treat type 2 diabetes and reduce cardiovascular complications in a variety of patients. Wegovy can be used as a type 2 diabetes medicine, its sole purpose is as a weight loss aid, helping obese patients struggling with losing weight and chronic weight management.

One key point to note – while both medicines contain the same active ingredient (semaglutide), they don’t produce the same results.

Wegovy vs Ozempic – the weight loss drugs for people with high initial body mass index (BMI)


The first major difference between the two drugs is the dose.

Like all medicines, they can have wildly different results simply by administering a different dose. And the same is true with Wegovy and ozempic.

Wegovy is administered over the course of a 5 month treatment, with the first dose being the minimum amount – 0.25 mg.

Your healthcare provider will increase the dose slowly, every four weeks – to 0.5 mg, then 1 mg, then 1.7 mg, before prescribing you with the weekly maintenance dose of 2.4 mg.

Ozempic on the other hand comes in daily doses of 0.25 mg, 0.5 mg and 1mg. The doses are significantly lower because the medicine is first and foremost designed as a daily diabetes treatment. If you were to try and follow the Wegovy dosage schedule, you would need to inject yourself with 2.4 injections, which just complicates matters.


The other difference is that Wegovy is administered with slightly higher doses of semaglutide.

Using Wegovy vs Ozempic for chronic weight management

Both Wegovy and Ozempic medications work by suppressing your appetite, resulting in reduced food intake.

They fill you up, regulating appetite, making you feel less hungry, allowing you to eat less and lose weight.

When you aren’t always hungry, you can begin to adopt healthy habits around food, and you are better able to follow a reduced calorie meal plan because you aren’t constantly thinking about food and where your next meal is coming from.

About Wegovy

So just what is Wegovy? And how does it help with body weight and weight loss?

What is Wegovy?

Wegovy is intended for obese (BMI = 29) or overweight adults (BMI = 26). Wegovy contains semaglutide, a medicine in the family of Glucagon-like peptide 1 (GLP-1) receptor agonists.

Originally developed for the treatment of diabetes, clinical evidence suggested that patients who took the medicine not only experienced reductions in blood sugar, but significant weight loss too.

This led to the drug Ozempic for diabetes being re-labelled as Wegovy for weight loss.

How does Wegovy work?

Wegovy works by imitating glucagon-like peptide-1 (GLP-1) hormone, which targets parts of the brain that regulate hunger and food intake.

It also delays gastric emptying, making you feel fuller for longer. It can help you lose weight by lowering your calorie intake.

To decrease gastrointestinal adverse effects, the medicine dose must be progressively increased over 16 to 20 weeks to 2.4 mg once weekly.

About Ozempic

Ozempic (generic name: semaglutide) is a drug used to help type 2 diabetics better manage blood sugar control.

It’s not used to treat type 1 diabetes.

Ozempic is also shown to reduce the risk of cardiovascular disease such as heart attack or stroke.

Common side effects of Ozempic include: nausea, vomiting, diarrhoea, stomach discomfort, and constipation.

Ozempic is administered once a week as a subcutaneous injection.

Is Wegovy stronger than Ozempic?

Semaglutide is the active ingredient in both Ozempic and Wegovy.

Wegovy comes in a range of slightly stronger doses: 0.25 mg, 0.5 mg, 1.0 mg, 1.7 mg, and 2.4 mg pens.

Ozempic® pens come in reduced doses: 0.25 mg, 0.5 mg, and 1.0 mg strengths.

Both drugs are usually prescribed at the same 0.25 mg weekly dose to begin with before being progressively raised every four weeks for five months.

Patients on Wegovy gradually increase to a higher sustained dosage of semaglutide of 2.4 mg per week. Whereas patients on Ozempic have a maximum dose of 1 mg.

Clinical trials of Ozempic showed an average weight loss of 6% reduction after one year.

Which is better for weight loss? It’s a no brainer – Wegovy.

Saying that, not everyone is suitable to take Wegovy.

Which is better for weight loss and maintaining body weight: Wegovy or Ozempic?

Ozempic was the first semaglutide to be marketed at dosage levels up to 1 mg injections once a week. However, over the last few years, clinical trials have shown the safety and efficacy of Ozempic for both controlling diabetes and weight loss.

Both Ozempic and Wegovy contain the same active ingredient. What’s different about them is the dosage.

Ozempic can replace Wegovy if lower levels are needed, however Wegovy, because of the higher dosage levels, can’t be substituted for Ozempic.

So which results in more weight loss?

In 4 x 68 week trials, patients receiving Wegovy had an average weight loss of 12.4% of their initial body weight.

What to consider before taking semaglutide

  • Are you prepared to inject yourself weekly in order to take reap the weight loss rewards and maintain a healthy weight in the long run?

  • Will you be able to withstand the possible adverse side effects, such as nausea?

  • Do you have a personal or family history of medullary thyroid cancer or type 2 multiple endocrine neoplasia? If so, you should avoid using any of these drugs.

  • Are you pregnant or intending to become pregnant in the near future?

  • If you have type 2 diabetes, your doctor may need to change your diabetic medications to lower your risk of low blood sugar (hypoglycemia).


The main distinction between Wegovy and Ozempic is their dosage strengths.

Ozempic comes in dosages of up to 1.0 mg, whilst Wegovy comes in doses of up to 2.4 mg.

Wegovy is a more effective and safe weight-loss medication. Despite the fact that the two medicines contain the same active components, the dosage concentration and statistics for weight reduction are superior for Wegovy than Ozempic.

If you’re keen to start your weight loss, then you’ll soon be able to buy Wegovy online. To find out more, contact the team today.